Allele Frequency Calculator

Allele Frequency Calculator

Calculate allele frequencies and test Hardy-Weinberg equilibrium

Note: This calculator determines allele frequencies, genotype frequencies, and tests for Hardy-Weinberg equilibrium in population genetics.

Genotype Counts

Analysis Type

Significance Level

Total Population Size
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Allele A Frequency (p)
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Allele a Frequency (q)
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Expected Genotype Frequencies
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Observed vs Expected
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Hardy-Weinberg Equilibrium Test

Enter parameters to see equilibrium test results.

Understanding Allele Frequencies

  • p: Frequency of dominant allele A
  • q: Frequency of recessive allele a (q = 1 - p)
  • p²: Expected frequency of AA genotype
  • 2pq: Expected frequency of Aa genotype
  • q²: Expected frequency of aa genotype

Population Genetics Guidelines

  • Ensure random mating in the population
  • Check for selection, mutation, and migration
  • Use appropriate sample sizes for statistical power
  • Consider multiple loci for comprehensive analysis
  • Account for population structure and subdivision
Important: This calculator assumes ideal conditions for Hardy-Weinberg equilibrium. Real populations may deviate due to selection, genetic drift, mutation, migration, and non-random mating. Always interpret results in the context of your specific study system.
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