PSA Doubling Time Calculator
Calculate PSA doubling time for prostate cancer progression assessment
Medical Disclaimer
This calculator is for educational purposes only. Always consult a healthcare professional for medical advice and diagnosis.
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PSA Doubling Time Calculation
About PSA Doubling Time
PSA doubling time is the time it takes for PSA levels to double and is a key prognostic factor in prostate cancer.
Doubling Time Formula:
DT = (Time × ln(2)) / ln(PSA2/PSA1)
Where:
- • Time = interval between measurements
- • PSA1 = initial PSA
- • PSA2 = final PSA
- • ln = natural logarithm
Interpretation:
- <3 months: Rapid progression
- 3-12 months: Moderate progression
- >12 months: Slow progression
Clinical Significance:
- • Prognostic indicator
- • Treatment response assessment
- • Active surveillance criteria
- • Survival prediction
Limitations:
- • Requires multiple measurements
- • Affected by treatment
- • PSA fluctuations
- • Not always linear
Professional Resources:
- • Urologist
- • Medical oncologist
- • Radiation oncologist
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