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TPA Calculator – Stroke Dosing
Alteplase Dosing for Acute Ischemic Stroke Management
Neurology Guidelines: Standard acute ischemic stroke tPA (Alteplase) dosing is $0.9\text{ mg/kg}$ (maximum total dose: $90\text{ mg}$). Administer $10\%$ as an IV bolus over 1 minute, and the remaining $90\%$ as a continuous infusion over 60 minutes. Enter patient weight below.
Patient Weight Input
Calculation Results
⚠️ Not medical advice. For neurology, emergency medicine, and clinical reference only. Acute ischemic stroke thrombolytic therapy, alteplase administration, and patient monitoring must be supervised strictly by an attending neurologist, emergency physician, or stroke team.